血液学の最新論文（2019年10月リリース分）New reports on Hematology
Leukemia
- Blood Toxicity and Response following CD19-specific CAR T cells in pediatric/young adult relapsed/refractory B-ALL. Blood. 2019 Oct 17. pii: blood.2019001641. doi: 10.1182/blood.2019001641. Curran KJ, Margossian S, Kernan NA, Silverman LB, Williams DA, Shukla NN, Kobos R, Forlenza C, Steinherz P, Prockop S, Boulad F, Spitzer B, Cancio MI, Boelens JJ, Kung AL, Szenes VZ, Park J, Sauter CS, Heller G, Wang X, Senechal B, O'Reilly RJ, Riviere I, Sadelain M, Brentjens RJ
- Blood Terminal Deoxynucleotidyl Transferase Promotes Acute Myeloid Leukemia By Priming FLT3-ITD Replication Slippage. Blood. 2019 Oct 17. pii: blood.2019001238. doi: 10.1182/blood.2019001238. Borrow J, Dyer SA, Akiki S, Griffiths MJ
- Blood Molecular Roulette: Nucleophosmin Mutations in AML are Orchestrated through N-Nucleotide Addition by TdT. Blood. 2019 Oct 17. pii: blood.2019001240. doi: 10.1182/blood.2019001240. Borrow J, Dyer SA, Akiki S, Griffiths MJ
- Blood CircMYBL2, a circRNA from MYBL2, Regulates FLT3 Translation by Recruiting PTBP1 to Promote FLT3-ITD AML Progression. 134(18):1533-1546 Yu-Meng Sun, Wen-Tao Wang, Zhan-Cheng Zeng, Tian-Qi Chen, Cai Han, Qi Pan, Wei Huang, Ke Fang, Lin-Yu Sun, Yan-Fei Zhou, Xue-Qun Luo, Chengwei Luo, Xin Du, Yue-Qin Chen
- Blood Improved survival of men 50 to 75 years old with acute myeloid leukemia over a 20-year period. 134(18):1558-1561 Gunnar Juliusson, Oskar Hagberg, Vladimir Lj Lazarevic, Emma Ölander, Petar Antunovic, Jörg Cammenga, Lovisa Wennström, Lars Möllgård, Mats Brune, Martin Jädersten, Stefan Deneberg, Sören Lehmann, Åsa Rangert Derolf, Martin Höglund, for the Swedish AML Registry
- Blood Rapid progression of adult T-cell leukemia/lymphoma as tumor-infiltrating Tregs after PD-1 blockade. 134(17):1406-1414 Daniel A. Rauch, Kevin C. Conlon, Murali Janakiram, Jonathan E. Brammer, John C. Harding, B. Hilda Ye, Xingxing Zang, Xiaoxin Ren, Sydney Olson, Xiaogang Cheng, Milos D. Miljkovic, Hemalatha Sundaramoorthi, Ancy Joseph, Zachary L. Skidmore, Obi Griffith, Malachi Griffith, Thomas A. Waldmann, Lee Ratner
- Blood Activated stromal cells transfer mitochondria to rescue acute lymphoblastic leukemia cells from oxidative stress. 134(17):1415-1429 Richard Burt, Aditi Dey, Sarah Aref, Melanie Aguiar, Ayse Akarca, Katharine Bailey, William Day, Steven Hooper, Amy Kirkwood, Kristina Kirschner, Soo-Wah Lee, Cristina Lo Celso, Jiten Manji, Marc R. Mansour, Teresa Marafioti, Rachel J. Mitchell, Robert C. Muirhead, Kenton Cheuk Yan Ng, Constandina Pospori, Ignazio Puccio, Krisztina Zuborne-Alapi, Erik Sahai, Adele K. Fielding
- Blood Germline DDX41 mutations define a significant entity within adult MDS/AML patients. 134(17):1441-1444 Marie Sébert, Marie Passet, Anna Raimbault, Ramy Rahmé, Emmanuel Raffoux, Flore Sicre de Fontbrune, Marco Cerrano, Samuel Quentin, Nadia Vasquez, Mélanie Da Costa, Nicolas Boissel, Hervé Dombret, Régis Peffault de Latour, Gérard Socié, Raphaël Itzykson, Pierre Fenaux, Jean Soulier, Lionel Adès, Emmanuelle Clappier
- Blood En-Abl-ing treatment of “Ph-like” ALL? 134(16):1277-1278 Adele K. Fielding
- Blood Suz12 inactivation cooperates with JAK3 mutant signaling in the development of T-cell acute lymphoblastic leukemia. 134(16):1323-1336 Michael Broux, Cristina Prieto, Sofie Demeyer, Marlies Vanden Bempt, Llucia Alberti-Servera, Inge Lodewijckx, Roel Vandepoel, Nicole Mentens, Olga Gielen, Kris Jacobs, Ellen Geerdens, Carmen Vicente, Charles E. de Bock, Jan Cools
- Blood Efficacy of tyrosine kinase inhibitors in Ph-like acute lymphoblastic leukemia harboring ABL-class rearrangements. 134(16):1351-1355 Ilaria Tanasi, Ibrahima Ba, Nicolas Sirvent, Thorsten Braun, Wendy Cuccuini, Paola Ballerini, Nicolas Duployez, Aline Tanguy-Schmidt, Jérôme Tamburini, Sébastien Maury, Eric Doré, Chantal Himberlin, Cédric Duclos, Patrice Chevallier, Philippe Rousselot, Massimiliano Bonifacio, Hélène Cavé, André Baruchel, Hervé Dombret, Jean Soulier, Judith Landman-Parker, Nicolas Boissel, Emmanuelle Clappier
- Blood Inherited genetic susceptibility to acute lymphoblastic leukemia in Down syndrome. 134(15):1227-1237 Austin L. Brown, Adam J. de Smith, Vincent U. Gant, Wenjian Yang, Michael E. Scheurer, Kyle M. Walsh, Jonathan M. Chernus, Noah A. Kallsen, Shanna A. Peyton, Gareth E. Davies, Erik A. Ehli, Naomi Winick, Nyla A. Heerema, Andrew J. Carroll, Michael J. Borowitz, Brent L. Wood, William L. Carroll, Elizabeth A. Raetz, Eleanor Feingold, Meenakshi Devidas, Lisa F. Barcellos, Helen M. Hansen, Libby Morimoto, Alice Y. Kang, Ivan Smirnov, Jasmine Healy, Caroline Laverdière, Daniel Sinnett, Jeffrey W. Taub, Jillian M. Birch, Pamela Thompson, Logan G. Spector, Maria S. Pombo-de-Oliveira, Andrew T. DeWan, Charles G. Mullighan, Stephen P. Hunger, Ching-Hon Pui, Mignon L. Loh, Michael E. Zwick, Catherine Metayer, Xiaomei Ma, Beth A. Mueller, Stephanie L. Sherman, Joseph L. Wiemels, Mary V. Relling, Jun J. Yang, Philip J. Lupo, Karen R. Rabin
- Blood Targeting PRMT1-mediated FLT3 methylation disrupts maintenance of MLL-rearranged acute lymphoblastic leukemia. 134(15):1257-1268 Yinghui Zhu, Xin He, Yi-Chun Lin, Haojie Dong, Lei Zhang, Xianwei Chen, Zhihao Wang, Yudao Shen, Min Li, Hanying Wang, Jie Sun, Le Xuan Nguyen, Han Zhang, Wenjuan Jiang, Yanzhong Yang, Jianjun Chen, Markus Müschen, Chun-Wei Chen, Marina Y. Konopleva, Weili Sun, Jian Jin, Nadia Carlesso, Guido Marcucci, Yun Luo, Ling Li
- Blood Simultaneous acute myeloid leukemia, multiple myeloma, and amyloidosis. 134(15):1270 Muhammad Umair Mushtaq, Daniel Rusch Matson
- Blood Consensus criteria for diagnosis, staging, and treatment response assessment of T-cell prolymphocytic leukemia. 134(14):1132-1143 Staber PB, Herling M, Bellido M, Jacobsen ED, Davids MS, Kadia TM, Shustov A, Tournilhac O, Bachy E, Zaja F, Porkka K, Hoermann G, Simonitsch-Klupp I, Haferlach C, Kubicek S, Mayerhoefer ME, Hopfinger G, Jaeger U, Dearden C
- Blood LMO2 activation by deacetylation is indispensable for hematopoiesis and T-ALL leukemogenesis. 134(14):1159-1175 Morishima T, Krahl AC, Nasri M, Xu Y, Aghaallaei N, Findik B, Klimiankou M, Ritter M, Hartmann MD, Gloeckner CJ, Stefanczyk S, Lindner C, Oswald B, Bernhard R, Hähnel K, Hermanutz-Klein U, Ebinger M, Handgretinger R, Casadei N, Welte K, Andre M, Müller P, Bajoghli B, Skokowa J
- Br J Haematol Spanish Guidelines for the use of targeted deep sequencing in myelodysplastic syndromes and chronic myelomonocytic leukaemia. Br J Haematol. 2019 Oct 16. doi: 10.1111/bjh.16175. Palomo L, Ibáñez M, Abáigar M, Vázquez I, Álvarez S, Cabezón M, Tazón-Vega B, Rapado I, Fuster-Tormo F, Cervera J, Benito R, Larrayoz MJ, Cigudosa JC, Zamora L, Valcárcel D, Cedena MT, Acha P, Hernández-Sánchez JM, Fernández-Mercado M, Sanz G, Hernández-Rivas JM, Calasanz MJ, Solé F, Such E; Spanish Group of MDS (GESMD)
- Br J Haematol Venetoclax-induced tumour lysis syndrome in acute myeloid leukaemia. Br J Haematol. 2019 Oct 16. doi: 10.1111/bjh.16235. Esparza S, Muluneh B, Galeotti J, Matson M, Richardson DR, Montgomery ND, Coombs CC, Jamieson K, Foster MC, Zeidner JF
- Br J Haematol Outcomes of acute lymphoblastic leukaemia in adolescent and young adult Korean patients. Br J Haematol. 2019 Oct 14. doi: 10.1111/bjh.16242. Kim YA, Ju HY, Park HJ, Lee NY, Lee HJ, Lee H, Ghang H
- Br J Haematol Graft-versus-host disease and graft-versus-leukaemia effects in secondary acute myeloid leukaemia: a retrospective, multicentre registry analysis from the Acute Leukaemia Working Party of the EBMT. Br J Haematol. 2019 Oct 14. doi: 10.1111/bjh.16185. Baron F, Labopin M, Savani BN, Beohou E, Niederwieser D, Eder M, Potter V, Kröger N, Beelen D, Socié G, Itälä-Remes M, Bornhäuser M, Mohty M, Nagler A
- Br J Haematol Patients aged less than 3 years with acute myeloid leukaemia characterize a molecularly and clinically distinct subgroup. Br J Haematol. 2019 Oct 14. doi: 10.1111/bjh.16203. Hara Y, Shiba N, Yamato G, Ohki K, Tabuchi K, Sotomatsu M, Tomizawa D, Kinoshita A, Arakawa H, Saito AM, Kiyokawa N, Tawa A, Horibe K, Taga T, Adachi S, Taki T, Hayashi Y
- Br J Haematol Retroviral sero-reactivity in LGL leukaemia patients and family members. Br J Haematol. 2019 Oct 14. doi: 10.1111/bjh.16223. Nyland SB, Feith DJ, Poss M, Olson TL, Krissinger DJ, Poiesz BJ, Ruscetti FW, Loughran TP Jr
- Br J Haematol Analysis of the clinical impact of NPM1 mutant allele burden in a large cohort of younger adult patients with acute myeloid leukaemia. Br J Haematol. 2019 Oct 8. doi: 10.1111/bjh.16239. Linch DC, Hills RK, Burnett AK, Russell N, Gale RE
- Br J Haematol TP53 mutations and relevance of expression of TP53 pathway genes in paediatric acute myeloid leukaemia. Br J Haematol. 2019 Oct 6. doi: 10.1111/bjh.16229. Cucchi DGJ, Bachas C, Klein K, Huttenhuis S, Zwaan CM, Ossenkoppele GJ, Janssen JMWM, Kaspers GL, Cloos J
- Br J Haematol Sudden blastic transformation in treatment-free remission chronic myeloid leukaemia. Br J Haematol. 2019 Oct 4. doi: 10.1111/bjh.16245. Alfayez M, Richard-Carpentier G, Jabbour E, Vishnu P, Naqvi K, Sasaki K, Cortes J, Pemmaraju N
- Br J Haematol Mutant allelic burden in acute myeloid leukaemia: Why bother? Br J Haematol. 2019 Oct 3. doi: 10.1111/bjh.16240. Touw IP, Sanders MA
- Br J Haematol Multi-dimensional analysis identifies an immune signature predicting response to decitabine treatment in elderly patients with AML. Br J Haematol. 2019 Oct 1. doi: 10.1111/bjh.16228. Zhao C, Jia B, Wang M, Schell TD, Claxton DF, Ehmann WC, Rybka WB, Mineishi S, Naik S, Songdej N, Sivik JM, Hohl RJ, Zeng H, Zheng H
- Br J Haematol Bone marrow metastases mimicking acute leukaemia. Br J Haematol. 2019 Oct 1. doi: 10.1111/bjh.16224. Chraïbi S, Vergé V, Micol JB
- Br J Haematol The concept of leukaemic stem cells in acute myeloid leukaemia 25 years on: hitting a moving target. 187(2):144-156 Hokland P, Woll PS, Hansen MC, Bill M
- Br J Haematol Differentiation syndrome in acute promyelocytic leukaemia. 187(2):157-162 Stahl M, Tallman MS
- Br J Haematol Essential role of PTPN11 mutation in enhanced haematopoietic differentiation potential of induced pluripotent stem cells of juvenile myelomonocytic leukaemia. 187(2):163-173 Shigemura T, Matsuda K, Kurata T, Sakashita K, Okuno Y, Muramatsu H, Yue F, Ebihara Y, Tsuji K, Sasaki K, Nakahata T, Nakazawa Y, Koike K
- Br J Haematol SIRT3 deacetylase activity confers chemoresistance in AML via regulation of mitochondrial oxidative phosphorylation. 187(1):49-64 Ma J, Liu B, Yu D, Zuo Y, Cai R, Yang J, Cheng J
- Br J Haematol Impact of genotype in relapsed and refractory acute myeloid leukaemia patients treated with clofarabine and cytarabine: a retrospective study. 187(1):65-72 Mondesir J, Alary AS, Sibon D, Willems L, Deau B, Suarez F, Hermine O, Fontenay M, Bouscary D, Kosmider O, Tamburini J
- Br J Haematol Distinct immunoglobulin heavy chain variable region gene repertoire and lower frequency of del(11q) in Taiwanese patients with chronic lymphocytic leukaemia. 187(1):82-92 Huang YJ, Kuo MC, Chang H, Wang PN, Wu JH, Huang YM, Ma MC, Tang TC, Kuo CY, Shih LY
- Haematologica RNAmut: robust identification of somatic mutations in acute myeloid leukemia using RNA-seq. Haematologica. 2019 Oct 24. pii: haematol.2019.230821. doi: 10.3324/haematol.2019.230821. Gu M, Zwiebel M, Ong SH, Boughton N, Nomdedeu J, Basheer F, Nannya Y, Quiros PM, Ogawa S, Cazzola M, Rad R, Butler AP, Vijayabaskar MS, Vassiliou G
- Haematologica The new small tyrosine-kinase inhibitor ARQ531 targets acute myeloid leukemia cells by disrupting multiple tumor-addicted programs. Haematologica. 2019 Oct 17. pii: haematol.2019.224956. doi: 10.3324/haematol.2019.224956. Soncini D, Orecchioni S, Ruberti S, Minetto P, Martinuzzi C, Agnelli L, Todoerti K, Cagnetta A, Miglino M, Clavio M, Contini P, Varaldo R, Bergamaschi M, Guolo F, Passalacqua M, Nencioni A, Monacelli F, Gobbi M, Neri A, Abbadessa G, Eathiraj S, Schwartz B, Bertolini F, Lemoli RM, Cea M
- Haematologica Disrupting the leukemia niche in the central nervous system attenuates leukemia chemoresistance. Haematologica. 2019 Oct 17. pii: haematol.2019.230334. doi: 10.3324/haematol.2019.230334. Jonart LM, Ebadi M, Basile P, Johnson K, Makori J, Gordon PM
- Haematologica Relapses and treatment-related events contributed equally to poor prognosis in children with ABL-class fusion positive B-cell acute lymphoblastic leukemia treated according to AIEOP-BFM protocols. Haematologica. 2019 Oct 10. pii: haematol.2019.231720. doi: 10.3324/haematol.2019.231720. Cario G, Leoni V, Conter V, Attarbaschi A, Zaliova M, Sramkova L, Cazzaniga G, Fazio G, Sutton R, Elitzur S, Izraeli S, Lauten M, Locatelli F, Basso G, Buldini B, Bergmann AK, Lentes J, Steinemann D, Göhring G, Schlegelberger B, Haas OA, Schewe D, Buchmann S, Moericke A, White D, Revesz T, Stanulla M, Mann G, Bodmer N, Arad-Cohen N, Zuna J, Valsecchi MG, Zimmermann M, Schrappe M, Biondi A
- Haematologica Acute erythroid leukemias have a distinct molecular hierarchy from non-erythroid acute myeloid leukemias. Haematologica. 2019 Oct 10. pii: haematol.2019.231142. doi: 10.3324/haematol.2019.231142. Cervera N, Lhoumeau AC, Adélaïde J, Guille A, Murati A, Mozziconacci MJ, Vey N, Birnbaum D, Gelsi-Boyer V
- Haematologica Sequential and combination treatments with novel agents in chronic lymphocytic leukemia. Haematologica. 2019 Oct 4. pii: haematol.2018.208603. doi: 10.3324/haematol.2018.208603. Fürstenau M, Hallek M, Eichhorst B
- Haematologica Yttrium-90-labeled anti-CD45 antibody followed by a reduced-intensity hematopoietic cell transplantation for patients with relapsed/refractory leukemia or myelodysplasia. Haematologica. 2019 Oct 3. pii: haematol.2019.229492. doi: 10.3324/haematol.2019.229492. Vo P, Gooley TA, Rajendran JG, Fisher DR, Orozco JJ, Green DJ, Gopal AK, Haaf R, Nartea M, Storb R, Appelbaum FR, Press OW, Pagel JM, Sandmaier BM
- Haematologica Inflammation regulates long non-coding RNA-PTTG1-1:1 in myeloid leukemia. Haematologica. 2019 Oct 3. pii: haematol.2019.217281. doi: 10.3324/haematol.2019.217281. Chateauvieux S, Gaigneaux A, Gérard D, Orsini M, Morceau F, Orlikova-Boyer B, Farge T, Récher C, Sarry JE, Dicato M, Diederich M
- Haematologica How I diagnose and manage Philadelphia chromosome-like acute lymphoblastic leukemia. Haematologica. 2019 Oct 3. pii: haematol.2018.207506. doi: 10.3324/haematol.2018.207506. Frisch A, Ofran Y
- Haematologica A laboratory-based scoring system predicts early treatment in Rai 0 chronic lymphocytic leukemia. Haematologica. 2019 Oct 3. pii: haematol.2019.228171. doi: 10.3324/haematol.2019.228171. Cohen JA, Rossi FM, Zucchetto A, Bomben R, Terzi-di-Bergamo L, Rabe KG, Degan M, Steffan A, Polesel J, Santinelli E, Innocenti I, Cutrona G, D' Arena G, Pozzato G, Zaja F, Chiarenza A, Rossi D, Di Raimondo F, Laurenti L, Gentile M, Morabito F, Neri A, Ferrarini M, Fegan CD, Pepper CJ, Del Poeta G, Parikh SA, Kay NE, Gattei V
- Haematologica A high-content cytokine screen identifies myostatin propeptide as a positive regulator of primitive chronic myeloid leukemia cells. Haematologica. 2019 Oct 3. pii: haematol.2019.220434. doi: 10.3324/haematol.2019.220434. von Palffy S, Landberg N, Sandén C, Zacharaki D, Shah M, Nakamichi N, Hansen N, Askmyr M, Lilljebjörn H, Rissler M, Karlsson C, Scheding S, Richter J, Eaves CJ, Bhatia R, Järås M, Fioretos T
- Haematologica IGHV mutational status and outcome for patients with chronic lymphocytic leukemia upon treatment: a Danish nationwide population-based study. Haematologica. 2019 Oct 3. pii: haematol.2019.220194. doi: 10.3324/haematol.2019.220194. Rotbain EC, Frederiksen H, Hjalgrim H, Rostgaard K, Jakupsdottir Egholm G, Zahedi B, Poulsen CB, Enggaard L, da Cunha-Bang C, Niemann CU
- Haematologica An intronic deletion in megakaryoblastic leukemia 1 is associated with hyperproliferation of B cells in triplets with Hodgkin lymphoma. Haematologica. 2019 Oct 3. pii: haematol.2019.216317. doi: 10.3324/haematol.2019.216317. Record J, Sendel A, Kritikou JS, Kuznetsov NV, Brauner H, He M, Nagy N, Oliveira MMS, Griseti E, Haase CB, Dahlström J, Boddul S, Wermeling F, Thrasher AJ, Liu C, Andersson J, Claesson HE, Winqvist O, Burns SO, Björkholm M, Westerberg LS
- Haematologica Calreticulin exposure on malignant blasts correlates with improved natural killer cell-mediated cytotoxicity in acute myeloid leukemia patients. Haematologica. 2019 Oct 3. pii: haematol.2019.223933. doi: 10.3324/haematol.2019.223933. Truxova I, Kasikova L, Salek C, Hensler M, Lysak D, Holicek P, Bilkova P, Holubova M, Chen X, Mikyskova R, Reinis M, Kovar M, Tomalova B, Kline JP, Galluzzi L, Spisek R, Fucikova J
- Haematologica p66Shc deficiency sets the scene for clinically aggressive chronic lymphocytic leukemia. 104(10):1914-1916 Rosenquist R
- Haematologica Proposed diagnostic criteria for classical chronic myelomonocytic leukemia (CMML), CMML variants and pre-CMML conditions. 104(10):1935-1949 Valent P, Orazi A, Savona MR, Patnaik MM, Onida F, van de Loosdrecht AA, Haase D, Haferlach T, Elena C, Pleyer L, Kern W, Pemovska T, Vladimer GI, Schanz J, Keller A, Lübbert M, Lion T, Sotlar K, Reiter A, De Witte T, Pfeilstöcker M, Geissler K, Padron E, Deininger M, Orfao A, Horny HP, Greenberg PL, Arber DA, Malcovati L, Bennett JM
- Haematologica Bone marrow endothelial cell-derived interleukin-4 contributes to thrombocytopenia in acute myeloid leukemia. 104(10):1950-1961 Gao A, Gong Y, Zhu C, Yang W, Li Q, Zhao M, Ma S, Li J, Hao S, Cheng H, Cheng T
- Haematologica Arrayed molecular barcoding identifies TNFSF13 as a positive regulator of acute myeloid leukemia-initiating cells. 104(10):2006-2016 Chapellier M, Peña-Martínez P, Ramakrishnan R, Eriksson M, Talkhoncheh MS, Orsmark-Pietras C, Lilljebjörn H, Högberg C, Hagström-Andersson A, Fioretos T, Larsson J, Järås M
- Haematologica Hematopoietic niche drives FLT3-ITD acute myeloid leukemia resistance to quizartinib via STAT5-and hypoxia-dependent upregulation of AXL. 104(10):2017-2027 Dumas PY, Naudin C, Martin-Lannerée S, Izac B, Casetti L, Mansier O, Rousseau B, Artus A, Dufossée M, Giese A, Dubus P, Pigneux A, Praloran V, Bidet A, Villacreces A, Guitart A, Milpied N, Kosmider O, Vigon I, Desplat V, Dusanter-Fourt I, Pasquet JM
- Haematologica A systematic literature review and meta-analysis of minimal residual disease as a prognostic indicator in adult B-cell acute lymphoblastic leukemia. 104(10):2028-2039 Bassan R, Brüggemann M, Radcliffe HS, Hartfield E, Kreuzbauer G, Wetten S
- Haematologica p66Shc deficiency in the Eμ-TCL1 mouse model of chronic lymphocytic leukemia enhances leukemogenesis by altering the chemokine receptor landscape. 104(10):2040-2052 Patrussi L, Capitani N, Ulivieri C, Manganaro N, Granai M, Cattaneo F, Kabanova A, Mundo L, Gobessi S, Frezzato F, Visentin A, Finetti F, Pelicci PG, D'Elios MM, Trentin L, Semenzato G, Leoncini L, Efremov DG, Baldari CT
- Haematologica Olaptesed pegol (NOX-A12) with bendamustine and rituximab: a phase IIa study in patients with relapsed/refractory chronic lymphocytic leukemia. 104(10):2053-2060 Steurer M, Montillo M, Scarfò L, Mauro FR, Andel J, Wildner S, Trentin L, Janssens A, Burgstaller S, Frömming A, Dümmler T, Riecke K, Baumann M, Beyer D, Vauléon S, Ghia P, Foà R, Caligaris-Cappio F, Gobbi M
- Haematologica NUTM1 is a recurrent fusion gene partner in B-cell precursor acute lymphoblastic leukemia associated with increased expression of genes on chromosome band 10p12.31-12.2. 104(10):e455-e459 Hormann FM, Hoogkamer AQ, Beverloo HB, Boeree A, Dingjan I, Wattel MM, Stam RW, Escherich G, Pieters R, den Boer ML, Boer JM
- Haematologica Efficiency of blinatumomab in a t(8;21) acute myeloid leukemia expressing CD19. 104(10):e487-e488 Plesa A, Labussière-Wallet H, Hayette S, Salles G, Thomas X, Sujobert P
- Haematologica IGHV1 status in chronic lymphocytic leukemia identify ethnic groups with an aggressive clinical course (Comment to Giudice ID, Foà R. Haematologica. 2019;104(2):219-221). 104(10):e493 Amato T, Granai M, Leoncini L, Bellan C
- J Clin Oncol Improved CNS Control of Childhood Acute Lymphoblastic Leukemia Without Cranial Irradiation: St Jude Total Therapy Study 16. J Clin Oncol. 2019 Oct 28:JCO1901692. doi: 10.1200/JCO.19.01692. Jeha S, Pei D, Choi J, Cheng C, Sandlund JT, Coustan-Smith E, Campana D, Inaba H, Rubnitz JE, Ribeiro RC, Gruber TA, Raimondi SC, Khan RB, Yang JJ, Mullighan CG, Downing JR, Evans WE, Relling MV, Pui CH
- J Clin Oncol Improving Stratification for Children With Late Bone Marrow B-Cell Acute Lymphoblastic Leukemia Relapses With Refined Response Classification and Integration of Genetics. J Clin Oncol. 2019 Oct 23:JCO1901694. doi: 10.1200/JCO.19.01694. Eckert C, Groeneveld-Krentz S, Kirschner-Schwabe R, Hagedorn N, Chen-Santel C, Bader P, Borkhardt A, Cario G, Escherich G, Panzer-Grümayer R, Astrahantseff K, Eggert A, Sramkova L, Attarbaschi A, Bourquin JP, Peters C, Henze G, von Stackelberg A; ALL-REZ BFM Trial Group
- J Clin Oncol Can Combination Targeted Therapy Bring About Another Paradigm Shift in Chronic Lymphocytic Leukemia? 37(30):2711-2713 Woyach JA
- J Clin Oncol Ibrutinib Plus Venetoclax in Relapsed/Refractory Chronic Lymphocytic Leukemia: The CLARITY Study. 37(30):2722-2729 Hillmen P, Rawstron AC, Brock K, Muñoz-Vicente S, Yates FJ, Bishop R, Boucher R, MacDonald D, Fegan C, McCaig A, Schuh A, Pettitt A, Gribben JG, Patten PEM, Devereux S, Bloor A, Fox CP, Forconi F, Munir T
- J Clin Oncol Chromosomal Abnormalities and Prognosis in NPM1-Mutated Acute Myeloid Leukemia: A Pooled Analysis of Individual Patient Data From Nine International Cohorts. 37(29):2632-2642 Angenendt L, Röllig C, Montesinos P, Martínez-Cuadrón D, Barragan E, García R, Botella C, Martínez P, Ravandi F, Kadia T, Kantarjian HM, Cortes J, Juliusson G, Lazarevic V, Höglund M, Lehmann S, Recher C, Pigneux A, Bertoli S, Dumas PY, Dombret H, Preudhomme C, Micol JB, Terré C, Ráčil Z, Novák J, Žák P, Wei AH, Tiong IS, Wall M, Estey E, Shaw C, Exeler R, Wagenführ L, Stölzel F, Thiede C, Stelljes M, Lenz G, Mikesch JH, Serve H, Ehninger G, Berdel WE, Kramer M, Krug U, Schliemann C
- J Clin Oncol Long-Term Risk of Infections After Treatment of Childhood Leukemia: A Population-Based Cohort Study Using Administrative Health Data. 37(29):2651-2660 Pelland-Marcotte MC, Pole JD, Hwee J, Sutradhar R, Science M, Nathan PC, Sung L
- Lancet Haematol Treosulfan or busulfan plus fludarabine as conditioning treatment before allogeneic haemopoietic stem cell transplantation for older patients with acute myeloid leukaemia or myelodysplastic syndrome (MC-FludT.14/L): a randomised, non-inferiority, phase 3 trial. Lancet Haematol. 2019 Oct 9. pii: S2352-3026(19)30157-7. doi: 10.1016/S2352-3026(19)30157-7. Beelen DW, Trenschel R, Stelljes M, Groth C, Masszi T, Reményi P, Wagner-Drouet EM, Hauptrock B, Dreger P, Luft T, Bethge W, Vogel W, Ciceri F, Peccatori J, Stölzel F, Schetelig J, Junghanß C, Grosse-Thie C, Michallet M, Labussiere-Wallet H, Schaefer-Eckart K, Dressler S, Grigoleit GU, Mielke S, Scheid C, Holtick U, Patriarca F, Medeot M, Rambaldi A, Micò MC, Niederwieser D, Franke GN, Hilgendorf I, Winkelmann NR, Russo D, Socié G, Peffault de Latour R, Holler E, Wolff D, Glass B, Casper J, Wulf G, Menzel H, Basara N, Bieniaszewska M, Stuhler G, Verbeek M, Grass S, Iori AP, Finke J, Benedetti F, Pichlmeier U, Hemmelmann C, Tribanek M, Klein A, Mylius HA, Baumgart J, Dzierzak-Mietla M, Markiewicz M
- Lancet Oncol Patient-reported quality of life after tisagenlecleucel infusion in children and young adults with relapsed or refractory B-cell acute lymphoblastic leukaemia: a global, single-arm, phase 2 trial. Lancet Oncol. 2019 Oct 9. pii: S1470-2045(19)30493-0. doi: 10.1016/S1470-2045(19)30493-0. Laetsch TW, Myers GD, Baruchel A, Dietz AC, Pulsipher MA, Bittencourt H, Buechner J, De Moerloose B, Davis KL, Nemecek E, Driscoll T, Mechinaud F, Boissel N, Rives S, Bader P, Peters C, Sabnis HS, Grupp SA, Yanik GA, Hiramatsu H, Stefanski HE, Rasouliyan L, Yi L, Shah S, Zhang J, Harris AC
- Leukemia Thiopurine-mediated impairment of hematopoietic stem and leukemia cells in Nudt15R138C knock-in mice. Leukemia. 2019 Oct 24. doi: 10.1038/s41375-019-0583-9. Tatsumi G, Kawahara M, Imai T, Nishishita-Asai A, Nishida A, Inatomi O, Yokoyama A, Kakuta Y, Kito K, Andoh A
- Leukemia A six-gene leukemic stem cell score identifies high risk pediatric acute myeloid leukemia. Leukemia. 2019 Oct 23. doi: 10.1038/s41375-019-0604-8. Elsayed AH, Rafiee R, Cao X, Raimondi S, Downing JR, Ribeiro R, Fan Y, Gruber TA, Baker S, Klco J, Rubnitz JE, Pounds S, Lamba JK
- Leukemia Comparison of minimal residual disease levels in bone marrow and peripheral blood in adult acute lymphoblastic leukemia. Leukemia. 2019 Oct 22. doi: 10.1038/s41375-019-0599-1. Kotrova M, Volland A, Kehden B, Trautmann H, Ritgen M, Wäsch R, Faul C, Viardot A, Schwartz S, Baldus CD, Gökbuget N, Brüggemann M
- Leukemia Enhanced expression of the sphingosine-1-phosphate-receptor-3 causes acute myelogenous leukemia in mice. Leukemia. 2019 Oct 21. doi: 10.1038/s41375-019-0577-7. Vorbach S, Gründer A, Zhou F, Koellerer C, Jutzi JS, Simoni M, Riccetti L, Valk PJ, Sanders MA, Müller-Tidow C, Nofer JR, Pahl HL, Potì F
- Leukemia How we use venetoclax with hypomethylating agents for the treatment of newly diagnosed patients with acute myeloid leukemia. Leukemia. 2019 Oct 18. doi: 10.1038/s41375-019-0612-8. Jonas BA, Pollyea DA
- Leukemia HLA-matched and HLA-haploidentical allogeneic CD19-directed chimeric antigen receptor T-cell infusions are feasible in relapsed or refractory B-cell acute lymphoblastic leukemia before hematopoietic stem cell transplantation. Leukemia. 2019 Oct 18. doi: 10.1038/s41375-019-0610-x. Jin X, Cao Y, Wang L, Sun R, Cheng L, He X, Xiao X, Jiang Y, Li Q, Zhang H, Lu W, Lyu C, Jiang Y, Meng J, Zhao M
- Leukemia Long-term efficacy and safety of first-line ibrutinib treatment for patients with CLL/SLL: 5 years of follow-up from the phase 3 RESONATE-2 study. Leukemia. 2019 Oct 18. doi: 10.1038/s41375-019-0602-x. Burger JA, Barr PM, Robak T, Owen C, Ghia P, Tedeschi A, Bairey O, Hillmen P, Coutre SE, Devereux S, Grosicki S, McCarthy H, Simpson D, Offner F, Moreno C, Dai S, Lal I, Dean JP, Kipps TJ
- Leukemia Gata2 deficiency delays leukemogenesis while contributing to aggressive leukemia phenotype in Cbfb-MYH11 knockin mice. Leukemia. 2019 Oct 17. doi: 10.1038/s41375-019-0605-7. Saida S, Zhen T, Kim E, Yu K, Lopez G, McReynolds LJ, Liu PP
- Leukemia Large granular lymphocytic leukemia coexists with myeloid clones and myelodysplastic syndrome. Leukemia. 2019 Oct 17. doi: 10.1038/s41375-019-0601-y. Durrani J, Awada H, Kishtagari A, Visconte V, Kerr C, Adema V, Nagata Y, Kuzmanovic T, Hong S, Patel B, Nazha A, Lichtin A, Mukherjee S, Saunthararajah Y, Carraway H, Sekeres M, Maciejewski JP
- Leukemia CD9 blockade suppresses disease progression of high-risk pediatric B-cell precursor acute lymphoblastic leukemia and enhances chemosensitivity. Leukemia. 2019 Oct 17. doi: 10.1038/s41375-019-0593-7. Leung KT, Zhang C, Chan KYY, Li K, Cheung JTK, Ng MHL, Zhang XB, Sit T, Lee WYW, Kang W, To KF, Yu JWS, Man TKF, Wang H, Tsang KS, Cheng FWT, Lam GKS, Chow TW, Leung AWK, Leung TF, Yuen PMP, Ng PC, Li CK
- Leukemia Integrated nuclear proteomics and transcriptomics identifies S100A4 as a therapeutic target in acute myeloid leukemia. Leukemia. 2019 Oct 14. doi: 10.1038/s41375-019-0596-4. Alanazi B, Munje CR, Rastogi N, Williamson AJK, Taylor S, Hole PS, Hodges M, Doyle M, Baker S, Gilkes AF, Knapper S, Pierce A, Whetton AD, Darley RL, Tonks A
- Leukemia Residual abdominal lymphadenopathy after intensive frontline chemoimmunotherapy is associated with inferior outcome independently of minimal residual disease status in chronic lymphocytic leukemia. Leukemia. 2019 Oct 14. doi: 10.1038/s41375-019-0597-3. Fürstenau M, Bahlo J, Fink AM, Lange E, Dreger P, Dreyling M, Hess G, Ritgen M, Kneba M, Döhner H, Stilgenbauer S, Wendtner CM, Goede V, Fischer K, Böttcher S, Hallek M, Eichhorst B
- Leukemia T-cell acute lymphoblastic leukemia in patients 1-45 years treated with the pediatric NOPHO ALL2008 protocol. Leukemia. 2019 Oct 14. doi: 10.1038/s41375-019-0598-2. Quist-Paulsen P, Toft N, Heyman M, Abrahamsson J, Griškevičius L, Hallböök H, Jónsson ÓG, Palk K, Vaitkeviciene G, Vettenranta K, Åsberg A, Frandsen TL, Opdahl S, Marquart HV, Siitonen S, Osnes LT, Hultdin M, Overgaard UM, Wartiovaara-Kautto U, Schmiegelow K
- Leukemia Long-term results of all-trans retinoic acid and arsenic trioxide in non-high-risk acute promyelocytic leukemia: update of the APL0406 Italian-German randomized trial. Leukemia. 2019 Oct 14. doi: 10.1038/s41375-019-0589-3. Cicconi L, Platzbecker U, Avvisati G, Paoloni F, Thiede C, Vignetti M, Fazi P, Ferrara F, Divona M, Albano F, Efficace F, Sborgia M, Di Bona E, Breccia M, Borlenghi E, Cairoli R, Rambaldi A, Melillo L, La Nasa G, Fiedler W, Brossart P, Hertenstein B, Salih HR, Annibali O, Wattad M, Lubbert M, Brandts CH, Hanel M, Rollig C, Schmitz N, Link H, Frairia C, Fozza C, Maria D'Arco A, Di Renzo N, Cortelezzi A, Fabbiano F, Dohner K, Ganser A, Dohner H, Amadori S, Mandelli F, Teresa Voso M, Ehninger G, Schlenk RF, Lo-Coco F
- Leukemia Circ-RPL15: a plasma circular RNA as novel oncogenic driver to promote progression of chronic lymphocytic leukemia. Leukemia. 2019 Oct 14. doi: 10.1038/s41375-019-0594-6. Wu Z, Sun H, Liu W, Zhu H, Fu J, Yang C, Fan L, Wang L, Liu Y, Xu W, Li J, Jin H
- Leukemia In Ph+BCR-ABL1P210+ acute lymphoblastic leukemia the e13a2 (B2A2) transcript is prevalent. Leukemia. 2019 Oct 8. doi: 10.1038/s41375-019-0591-9. Baccarani M, Iacobucci I, Chiaretti S, Foà' R, Balasubramanian P, Paietta E, Foroni L, Jeromin S, Izzo B, Spinelli O, Varma N, Menif S, Terragna C, Seth T, Bidet A, Coriu D, Lunghi F, Mayer J, Scappini B, Langabeer S, Maier J, Burt E, Candoni A, Albano F, Luppi M, Zupan I, Lion T, Zadro R, di Raimondo F, Popak B, Rege-Cambrin G, Annunziata M, Ayala A, Salinas-Viedma V, Ines Prado A, Milner B, Galimberti S, Janssen J, Polli V, Comba L, Borsellino B, Annibali O, Crugnola M, Passamonti F
- Leukemia Retention of CD19 intron 2 contributes to CART-19 resistance in leukemias with subclonal frameshift mutations in CD19. Leukemia. 2019 Oct 7. doi: 10.1038/s41375-019-0580-z. Asnani M, Hayer KE, Naqvi AS, Zheng S, Yang SY, Oldridge D, Ibrahim F, Maragkakis M, Gazzara MR, Black KL, Bagashev A, Taylor D, Mourelatos Z, Grupp SA, Barrett D, Maris JM, Sotillo E, Barash Y, Thomas-Tikhonenko A
- Leukemia PMN-MDSC are a new target to rescue graft-versus-leukemia activity of NK cells in haplo-HSC transplantation. Leukemia. 2019 Oct 4. doi: 10.1038/s41375-019-0585-7. Tumino N, Besi F, Di Pace AL, Mariotti FR, Merli P, Li Pira G, Galaverna F, Pitisci A, Ingegnere T, Pelosi A, Quatrini L, Munari E, Locatelli F, Moretta L, Vacca P
- Leukemia Early hospital discharge after intensive induction chemotherapy for adults with acute myeloid leukemia or other high-grade myeloid neoplasm. Leukemia. 2019 Oct 4. doi: 10.1038/s41375-019-0586-6. Halpern AB, Howard NP, Othus M, Hendrie PC, Baclig NV, Buckley SA, Percival MM, Becker PS, Scott BL, Oehler VG, Gernsheimer TB, Keel SB, Orozco JJ, Cassaday RD, Shustov AR, Hartley GA, Welch VL, Estey EH, Walter RB
- Leukemia Hematopoietic stem cell transplantation for children with acute myeloid leukemia-results of the AML SCT-BFM 2007 trial. Leukemia. 2019 Oct 2. doi: 10.1038/s41375-019-0584-8. Sauer MG, Lang PJ, Albert MH, Bader P, Creutzig U, Eyrich M, Greil J, Gruhn B, Holter W, Klingebiel T, Kremens B, von der Leyen H, Mauz-Körholz C, Meisel R, Mischke K, Müller I, Niemeyer CM, Peters C, Pohler C, Reinhardt D, Burkhardt B, Schlegel PG, Schulz AS, Schrum J, Sedlacek P, Strahm B, Woessmann W, Handgretinger R, Zimmermann M, Borkhardt A
- Leukemia Functional characterization of BRCC3 mutations in acute myeloid leukemia with t(8;21)(q22;q22.1). Leukemia. 2019 Oct 1. doi: 10.1038/s41375-019-0578-6. Meyer T, Jahn N, Lindner S, Röhner L, Dolnik A, Weber D, Scheffold A, Köpff S, Paschka P, Gaidzik VI, Heckl D, Wiese S, Ebert BL, Döhner H, Bullinger L, Döhner K, Krönke J
- Leukemia The acetyltransferase GCN5 maintains ATRA-resistance in non-APL AML. Leukemia. 2019 Oct 1. doi: 10.1038/s41375-019-0581-y. Kahl M, Brioli A, Bens M, Perner F, Kresinsky A, Schnetzke U, Hinze A, Sbirkov Y, Stengel S, Simonetti G, Martinelli G, Petrie K, Zelent A, Böhmer FD, Groth M, Ernst T, Heidel FH, Scholl S, Hochhaus A, Schenk T
- Leukemia Chronic myeloid leukemia: the concepts of resistance and persistence and the relationship with the BCR-ABL1 transcript type. 33(10):2358-2364 Baccarani M, Rosti G, Soverini S
- Leukemia Blocking ATM-dependent NF-κB pathway overcomes niche protection and improves chemotherapy response in acute lymphoblastic leukemia. 33(10):2365-2378 Chen YL, Tang C, Zhang MY, Huang WL, Xu Y, Sun HY, Yang F, Song LL, Wang H, Mu LL, Li MH, Zheng WW, Miao Y, Ding LX, Li BS, Shen SH, Liu SL, Li H, Zhu ZQ, Chen HW, Tang ZH, Chen J, Hong DL, Chen HZ, Duan CW, Zhou BS
- Leukemia CD8+ T cells expand stem and progenitor cells in favorable but not adverse risk acute myeloid leukemia. 33(10):2379-2392 Radpour R, Riether C, Simillion C, Höpner S, Bruggmann R, Ochsenbein AF
- Leukemia Quality of life and mood of older patients with acute myeloid leukemia (AML) receiving intensive and non-intensive chemotherapy. 33(10):2393-2402 El-Jawahri A, Abel GA, Traeger L, Waldman L, Markovitz N, VanDusen H, Fathi A, Steensma DP, LeBlanc TW, Horick NK, DeAngelo DJ, Wadleigh M, Hobbs G, Foster J, Brunner AM, Amrein P, Stone RM, Temel JS, Greer JA
- Leukemia Biology and prognostic impact of clonal plasmacytoid dendritic cells in chronic myelomonocytic leukemia. 33(10):2466-2480 Lucas N, Duchmann M, Rameau P, Noël F, Michea P, Saada V, Kosmider O, Pierron G, Fernandez-Zapico ME, Howard MT, King RL, Niyongere S, Diop MK, Fenaux P, Itzykson R, Willekens C, Ribrag V, Fontenay M, Padron E, Soumelis V, Droin N, Patnaik MM, Solary E
- Leukemia Phase 1 first-in-human trial of the anti-CD37 antibody BI 836826 in relapsed/refractory chronic lymphocytic leukemia. 33(10):2531-2535 Stilgenbauer S, Aurran Schleinitz T, Eichhorst B, Lang F, Offner F, Rossi JF, Schroyens W, Van Den Neste E, Ysebaert L, von Wangenheim U, Ursula Kress U, Blum P, Zenz T
- Leukemia getITD for FLT3-ITD-based MRD monitoring in AML. 33(10):2535-2539 Blätte TJ, Schmalbrock LK, Skambraks S, Lux S, Cocciardi S, Dolnik A, Döhner H, Döhner K, Bullinger L
- Leukemia Elevated expression of S100A8 and S100A9 correlates with resistance to the BCL-2 inhibitor venetoclax in AML. 33(10):2548-2553 Karjalainen R, Liu M, Kumar A, He L, Malani D, Parsons A, Kontro M, Kallioniemi O, Porkka K, Heckman CA
- N Engl J Med Gilteritinib or Chemotherapy for Relapsed or Refractory FLT3-Mutated AML. 381(18):1728-1740 Perl AE, Martinelli G, Cortes JE, Neubauer A, Berman E, Paolini S, Montesinos P, Baer MR, Larson RA, Ustun C, Fabbiano F, Erba HP, Di Stasi A, Stuart R, Olin R, Kasner M, Ciceri F, Chou WC, Podoltsev N, Recher C, Yokoyama H, Hosono N, Yoon SS, Lee JH, Pardee T, Fathi AT, Liu C, Hasabou N, Liu X, Bahceci E, Levis MJ
Lymphoma
- Blood CD137 deficiency causes immune dysregulation with predisposition to lymphomagenesis. 134(18):1510-1516 Ido Somekh, Marini Thian, David Medgyesi, Nesrin Gülez, Thomas Magg, Alejandro Gallón Duque, Tali Stauber, Atar Lev, Ferah Genel, Ekrem Unal, Amos J. Simon, Yu Nee Lee, Artem Kalinichenko, Jasmin Dmytrus, Michael J. Kraakman, Ginette Schiby, Meino Rohlfs, Jeffrey M. Jacobson, Erdener Özer, Ömer Akcal, Raffaele Conca, Türkan Patiroglu, Musa Karakukcu, Alper Ozcan, Tala Shahin, Eliana Appella, Megumi Tatematsu, Catalina Martinez-Jaramillo, Ivan K. Chinn, Jordan S. Orange, Claudia Milena Trujillo-Vargas, José Luis Franco, Fabian Hauck, Raz Somech, Christoph Klein, Kaan Boztug
- Blood Skin colonization by circulating neoplastic clones in cutaneous T-cell lymphoma. 134(18):1517-1527 Aishwarya Iyer, Dylan Hennessey, Sandra O’Keefe, Jordan Patterson, Weiwei Wang, Gane Ka-Shu Wong, Robert Gniadecki
- Blood The double-hit signature identifies double-hit diffuse large B-cell lymphoma with genetic events cryptic to FISH. 134(18):1528-1532 Laura K. Hilton, Jeffrey Tang, Susana Ben-Neriah, Miguel Alcaide, Aixiang Jiang, Bruno M. Grande, Christopher K. Rushton, Merrill Boyle, Barbara Meissner, David W. Scott, Ryan D. Morin
- Blood TFH lymphomas: the times they aza-changin’? 134(17):1364-1365 David M. Weinstock, Steven M. Horwitz
- Blood Optimizing treatment of HIV-associated lymphoma. 134(17):1385-1394 Ariela Noy
- Blood Rapid progression of adult T-cell leukemia/lymphoma as tumor-infiltrating Tregs after PD-1 blockade. 134(17):1406-1414 Daniel A. Rauch, Kevin C. Conlon, Murali Janakiram, Jonathan E. Brammer, John C. Harding, B. Hilda Ye, Xingxing Zang, Xiaoxin Ren, Sydney Olson, Xiaogang Cheng, Milos D. Miljkovic, Hemalatha Sundaramoorthi, Ancy Joseph, Zachary L. Skidmore, Obi Griffith, Malachi Griffith, Thomas A. Waldmann, Lee Ratner
- Blood Targeted inhibition of CD47-SIRPα requires Fc-FcγR interactions to maximize activity in T-cell lymphomas. 134(17):1430-1440 Salvia Jain, Alexandria Van Scoyk, Elizabeth A. Morgan, Andrew Matthews, Kristen Stevenson, Gail Newton, Foster Powers, Anu Autio, Abner Louissaint, Jr, Guillemette Pontini, Jon C. Aster, Francis W. Luscinskas, David M. Weinstock
- Blood A rare case of leukemic anaplastic large cell lymphoma with the variant translocation t(X;2). 134(17):1480 Giulia Tueur, Gregory Lazarian
- Blood Impact of concurrent indolent lymphoma on the clinical outcome of newly diagnosed diffuse large B-cell lymphoma. 134(16):1289-1297 Yucai Wang, Brian K. Link, Thomas E. Witzig, Matthew J. Maurer, Cristine Allmer, Rebecca L. King, Andrew L. Feldman, Thomas M. Habermann, Stephen M. Ansell, Susan L. Slager, James R. Cerhan, Grzegorz S. Nowakowski
- Blood PET-adapted treatment of Hodgkin lymphoma. 134(15):1200-1201 Martin Hutchings
- Blood Five-year follow-up of SWOG S0816: limitations and values of a PET-adapted approach with stage III/IV Hodgkin lymphoma. 134(15):1238-1246 Deborah M. Stephens, Hongli Li, Heiko Schöder, David J. Straus, Craig H. Moskowitz, Michael LeBlanc, Lisa M. Rimsza, Nancy L. Bartlett, Andrew M. Evens, Ann S. LaCasce, Paul M. Barr, Michael V. Knopp, Eric D. Hsi, John P. Leonard, Brad S. Kahl, Sonali M. Smith, Jonathan W. Friedberg
- Blood Pembrolizumab in relapsed or refractory Hodgkin lymphoma: 2-year follow-up of KEYNOTE-087. 134(14):1144-1153 Chen R, Zinzani PL, Lee HJ, Armand P, Johnson NA, Brice P, Radford J, Ribrag V, Molin D, Vassilakopoulos TP, Tomita A, von Tresckow B, Shipp MA, Lin J, Kim E, Nahar A, Balakumaran A, Moskowitz CH
- Br J Haematol Autoimmune conditions and primary central nervous system lymphoma risk among older adults. Br J Haematol. 2019 Oct 17. doi: 10.1111/bjh.16222. Mahale P, Herr MM, Engels EA, Pfeiffer RM, Shiels MS
- Br J Haematol No excess long-term mortality in stage I-IIA Hodgkin lymphoma patients treated with ABVD and limited field radiotherapy. Br J Haematol. 2019 Oct 14. doi: 10.1111/bjh.16232. Lagerlöf I, Holte H, Glimelius I, Björkholm M, Enblad G, Erlanson M, Fluge Ø, Fohlin H, Fosså A, Goldkuhl C, Gustavsson A, Johansson AS, Linderoth J, Nome O, Palma M, Åkesson L, Østenstad B, Raud C, Glimelius B, Molin D
- Br J Haematol Brentuximab vedotin for the treatment of patients with relapsed or refractory Hodgkin lymphoma after autologous stem cell transplantation. Br J Haematol. 2019 Oct 6. doi: 10.1111/bjh.16201. Kaloyannidis P, Hertzberg M, Webb K, Zomas A, Schrover R, Hurst M, Jacob I, Nikoglou T, Connors JM
- Br J Haematol Safety of switching from intravenous to subcutaneous rituximab during first-line treatment of patients with non-Hodgkin lymphoma: the Spanish population of the MabRella study. Br J Haematol. 2019 Oct 1. doi: 10.1111/bjh.16227. García-Muñoz R, Quero C, Pérez-Persona E, Domingo-García A, Pérez-López C, Villaescusa-de-la-Rosa T, Martínez-Castro AM, Arguiñano-Pérez JM, Parra-Cuadrado JF, Panizo C
- Br J Haematol Hodgkin lymphoma infiltration with associated haemophagocytosis in bone marrow films. 187(2):138 Demagny J, Guiheneuf E, Joris M, Garçon L, Harrivel V
- Br J Haematol Outcomes of synchronous systemic and central nervous system (CNS) involvement of diffuse large B-cell lymphoma are dictated by the CNS disease: a collaborative study of the Australasian Lymphoma Alliance. 187(2):174-184 Wight JC, Yue M, Keane C, Johnston A, Linton K, Chin C, Wai SH, Talaulikar D, Gasiorowski R, Cheah CY, Gregory GP, Dickinson M, Minson A, Coombes C, Ku M, Lam S, Hawkes EA
- Br J Haematol The impact of diagnostic wait time on the survival of patients with diffuse large B-cell lymphoma: effect modification by the International Prognostic Index. 187(2):195-205 Lee S, Fujita K, Negoro E, Morishita T, Yamauchi H, Oiwa K, Ueda T, Yamauchi T
- Br J Haematol Bone marrow involvement by monomorphic epitheliotropic intestinal T-cell lymphoma. 187(1):10 Ikeda C, Maruyama D, Oka H, Fujino T, Maeshima AM, Matsushita H
- Br J Haematol Response-adapted therapy for the treatment of children with newly diagnosed high risk Hodgkin lymphoma (AHOD0831): a report from the Children’s Oncology Group. 187(1):39-48 Kelly KM, Cole PD, Pei Q, Bush R, Roberts KB, Hodgson DC, McCarten KM, Cho SY, Schwartz C
- Br J Haematol Comprehensive geriatric assessment is useful in an elderly Australian population with diffuse large B-cell lymphoma receiving rituximab-chemotherapy combinations. 187(1):73-81 Ong DM, Ashby M, Grigg A, Gard G, Ng ZY, Huang HE, Chong YS, Cheah CY, Devitt B, Chong G, Loh Z, Mo A, Hawkes EA
- Haematologica Quantification of minimal disseminated disease by quantitative PCR and digital PCR for NPM-ALK as prognostic factor in children with anaplastic large cell lymphoma. Haematologica. 2019 Oct 24. pii: haematol.2019.232314. doi: 10.3324/haematol.2019.232314. Damm-Welk C, Kutscher N, Zimmermann M, Attarbaschi A, Schieferstein J, Knörr F, Oschlies I, Klapper W, Woessmann W
- Haematologica DA-EPOCH-R combined with high-dose methotrexate in patients with newly diagnosed stage II-IV CD5-positive diffuse large B-cell lymphoma: a single-arm, open-label, phase 2 study. Haematologica. 2019 Oct 24. pii: haematol.2019.231076. doi: 10.3324/haematol.2019.231076. Miyazaki K, Asano N, Yamada T, Miyawaki K, Sakai R, Igarashi T, Nishikori M, Ohata K, Sunami K, Yoshida I, Yamamoto G, Takahashi N, Okamoto M, Yano H, Nishimura Y, Tamaru S, Nishikawa M, Izutsu K, Kinoshita T, Suzumiya J, Ohshima K, Kato K, Katayama N, Yamaguchi M; CD5+ DLBCL Treatment Study Group
- Haematologica Specific interactions of BCL-2 family proteins mediate sensitivity to BH3-mimetics in diffuse large B-cell lymphoma. Haematologica. 2019 Oct 10. pii: haematol.2019.220525. doi: 10.3324/haematol.2019.220525. Smith VM, Dietz A, Henz K, Bruecher D, Jackson R, Kowald L, van Wijk SJL, Jayne S, Macip S, Fulda S, Dyer MJS, Vogler M
- Haematologica Pre-treatment maximum standardized uptake value predicts outcome after frontline therapy in patients with advanced stage follicular lymphoma. Haematologica. 2019 Oct 10. pii: haematol.2019.230649. doi: 10.3324/haematol.2019.230649. Strati P, Ahmed MAA, Fowler N, Nastoupil LJ, Samaniego F, Fayad LE, Hagemeister FB, Romaguera JE, Rodriguez A, Wang M, Westin JR, Cheah C, Noorani M, Feng L, Davis RE, Neelapu SS
- Haematologica An intronic deletion in megakaryoblastic leukemia 1 is associated with hyperproliferation of B cells in triplets with Hodgkin lymphoma. Haematologica. 2019 Oct 3. pii: haematol.2019.216317. doi: 10.3324/haematol.2019.216317. Record J, Sendel A, Kritikou JS, Kuznetsov NV, Brauner H, He M, Nagy N, Oliveira MMS, Griseti E, Haase CB, Dahlström J, Boddul S, Wermeling F, Thrasher AJ, Liu C, Andersson J, Claesson HE, Winqvist O, Burns SO, Björkholm M, Westerberg LS
- Haematologica A clinico-molecular predictor identifies follicular lymphoma patients at risk of early transformation after first-line immunotherapy. 104(10):e460-e464 Steen CB, Leich E, Myklebust JH, Lockmer S, Wise JF, Wahlin BE, Østenstad B, Liestøl K, Kimby E, Rosenwald A, Smeland EB, Holte H, Lingjærde OC, Brodtkorb M
- Haematologica Clonal sequence tracking reveals TET2-mutated extranodal NK/T-cell lymphoma disseminated independent of Epstein Barr virus. 104(10):e489-e492 Yuan CT, Huang TC, Chuang CC, Chuang YK, Tsai JH, Liau JY, Lin CW, Tang JL
- J Clin Oncol Long-Term Follow-Up of Patients With Nodular Lymphocyte-Predominant Hodgkin Lymphoma Treated in the HD7 to HD15 Trials: A Report From the German Hodgkin Study Group. J Clin Oncol. 2019 Oct 18:JCO1900986. doi: 10.1200/JCO.19.00986. Eichenauer DA, Plütschow A, Fuchs M, Sasse S, Baues C, Böll B, von Tresckow B, Diehl V, Borchmann P, Engert A
- J Clin Oncol Pretreatment Vitamin D Deficiency Is Associated With Impaired Progression-Free and Overall Survival in Hodgkin Lymphoma. J Clin Oncol. 2019 Oct 17:JCO1900985. doi: 10.1200/JCO.19.00985. Borchmann S, Cirillo M, Goergen H, Meder L, Sasse S, Kreissl S, Bröckelmann PJ, von Tresckow B, Fuchs M, Ullrich RT, Engert A
- J Clin Oncol Pembrolizumab in Relapsed or Refractory Primary Mediastinal Large B-Cell Lymphoma. J Clin Oncol. 2019 Oct 14:JCO1901389. doi: 10.1200/JCO.19.01389. Armand P, Rodig S, Melnichenko V, Thieblemont C, Bouabdallah K, Tumyan G, Özcan M, Portino S, Fogliatto L, Caballero MD, Walewski J, Gulbas Z, Ribrag V, Christian B, Perini GF, Salles G, Svoboda J, Zain J, Patel S, Chen PH, Ligon AH, Ouyang J, Neuberg D, Redd R, Chatterjee A, Balakumaran A, Orlowski R, Shipp M, Zinzani PL
- J Clin Oncol Late Health Outcomes After Contemporary Lymphome Malin de Burkitt Therapy for Mature B-Cell Non-Hodgkin Lymphoma: A Report From the Childhood Cancer Survivor Study. 37(28):2556-2570 Ehrhardt MJ, Chen Y, Sandlund JT, Bluhm EC, Hayashi RJ, Becktell K, Leisenring WM, Metzger ML, Ness KK, Krull KR, Oeffinger KC, Gibson TM, Cairo MS, Gross TG, Robison LL, Armstrong GT, Yasui Y, Hudson MM, Mulrooney DA
- Leukemia Hematopoietic stem cell transplantation for adults with T-cell lymphoblastic lymphoma: can we successfully step into the era of precision medicine? Leukemia. 2019 Oct 22. doi: 10.1038/s41375-019-0608-4. Young KH
- Leukemia Targeting BCL-W and BCL-XL as a therapeutic strategy for Hodgkin lymphoma. Leukemia. 2019 Oct 21. doi: 10.1038/s41375-019-0611-9. Adams CM, Mitra R, Vogel AN, Liu J, Gong JZ, Eischen CM
- Leukemia Rituximab in newly diagnosed stage IA nodular lymphocyte-predominant Hodgkin lymphoma: long-term follow-up of a phase 2 study from the German Hodgkin Study Group. Leukemia. 2019 Oct 21. doi: 10.1038/s41375-019-0609-3. Eichenauer DA, Plütschow A, Fuchs M, Hartmann S, Hansmann ML, Böll B, von Tresckow B, Borchmann P, Engert A
- Leukemia T cells redirected against Igβ for the immunotherapy of B cell lymphoma. Leukemia. 2019 Oct 17. doi: 10.1038/s41375-019-0607-5. Jiang D, Tian X, Bian X, Zhu T, Qin H, Zhang R, Xu Y, Pan Z, Huang H, Fu J, Wu D, Chu J
- Leukemia Inhibition of SYK or BTK augments venetoclax sensitivity in SHP1-negative/BCL-2-positive diffuse large B-cell lymphoma. 33(10):2416-2428 Sasi BK, Martines C, Xerxa E, Porro F, Kalkan H, Fazio R, Turkalj S, Bojnik E, Pyrzynska B, Stachura J, Zerrouqi A, Bobrowicz M, Winiarska M, Priebe V, Bertoni F, Mansouri L, Rosenquist R, Efremov DG
- Leukemia Transient stabilization, rather than inhibition, of MYC amplifies extrinsic apoptosis and therapeutic responses in refractory B-cell lymphoma. 33(10):2429-2441 Harrington CT, Sotillo E, Robert A, Hayer KE, Bogusz AM, Psathas J, Yu D, Taylor D, Dang CV, Klein P, Hogarty MD, Geoerger B, El-Deiry WS, Wiels J, Thomas-Tikhonenko A
- Leukemia CSF1R and BTK inhibitions as novel strategies to disrupt the dialog between mantle cell lymphoma and macrophages. 33(10):2442-2453 Papin A, Tessoulin B, Bellanger C, Moreau A, Le Bris Y, Maisonneuve H, Moreau P, Touzeau C, Amiot M, Pellat-Deceunynck C, Le Gouill S, Chiron D
- Leukemia Prognostic and predictive value of a microRNA signature in adults with T-cell lymphoblastic lymphoma. 33(10):2454-2465 Tian XP, Huang WJ, Huang HQ, Liu YH, Wang L, Zhang X, Lin TY, Rao HL, Li M, Liu F, Zhang F, Zhong LY, Liang L, Lan XL, Li J, Liao B, Li ZH, Tang QL, Liang Q, Shao CK, Zhai QL, Cheng RF, Sun Q, Ru K, Gu X, Lin XN, Yi K, Shuang YR, Chen XD, Dong W, Sang W, Sun C, Liu H, Zhu ZG, Rao J, Guo QN, Zhou Y, Meng XL, Zhu Y, Hu CL, Jiang YR, Zhang Y, Gao HY, He WJ, Xia ZJ, Wu CL, Zhang MY, Wang HY, Xie D, Cai QQ
- Leukemia Safety and feasibility of chimeric antigen receptor T cell therapy after allogeneic hematopoietic cell transplantation in relapsed/ refractory B cell non-Hodgkin lymphoma. 33(10):2540-2544 Jain T, Sauter CS, Shah GL, Maloy MA, Chan J, Scordo M, Avecilla ST, Batlevi Y, Dahi PB, Batlevi CW, Lia Palomba M, Giralt SA, Perales MA
Myeloma
- Blood Extramedullary lesions to the pericardium and right atrium in refractory multiple myeloma. 134(18):1562 Tomoaki Fukae, Daihiko Hakuno
- Blood The great masquerader mimicking plasma cell myeloma. 134(17):1481 Joo Y. Song, Christiane Querfeld
- Blood Bortezomib, lenalidomide, and dexamethasone as induction therapy prior to autologous transplant in multiple myeloma. 134(16):1337-1345 Laura Rosiñol, Albert Oriol, Rafael Rios, Anna Sureda, María Jesús Blanchard, Miguel Teodoro Hernández, Rafael Martínez-Martínez, Jose M. Moraleda, Isidro Jarque, Juan Bargay, Mercedes Gironella, Felipe de Arriba, Luis Palomera, Yolanda González-Montes, Josep M. Martí, Isabel Krsnik, Jose M. Arguiñano, Maria Esther González, Ana Pilar González, Luis Felipe Casado, Lucia López-Anglada, Bruno Paiva, Maria-Victoria Mateos, Jesus F. San Miguel, Juan-José Lahuerta, Joan Bladé
- Blood The α-emitter astatine-211 targeted to CD38 can eradicate multiple myeloma in a disseminated disease model. 134(15):1247-1256 Shyril O’Steen, Melissa L. Comstock, Johnnie J. Orozco, Donald K. Hamlin, D. Scott Wilbur, Jon C. Jones, Aimee Kenoyer, Margaret E. Nartea, Yukang Lin, Brian W. Miller, Theodore A. Gooley, Sherilyn A. Tuazon, Brian G. Till, Ajay K. Gopal, Brenda M. Sandmaier, Oliver W. Press, Damian J. Green
- Blood Simultaneous acute myeloid leukemia, multiple myeloma, and amyloidosis. 134(15):1270 Muhammad Umair Mushtaq, Daniel Rusch Matson
- Blood Myeloma’s sound of silencing. 134(14):1116-1117 Boise LH
- Blood PHF19 promotes multiple myeloma tumorigenicity through PRC2 activation and broad H3K27me3 domain formation. 134(14):1176-1189 Ren Z, Ahn JH, Liu H, Tsai YH, Bhanu NV, Koss B, Allison DF, Ma A, Storey AJ, Wang P, Mackintosh SG, Edmondson RD, Groen RWJ, Martens AC, Garcia BA, Tackett AJ, Jin J, Cai L, Zheng D, Wang GG
- Br J Haematol Cystic lung disease with kappa light chain deposition in newly diagnosed multiple myeloma. Br J Haematol. 2019 Oct 17. doi: 10.1111/bjh.16236. Clayden RC, Macdonald D, Oikonomou A, Cheung MC
- Br J Haematol Pomalidomide plus low-dose dexamethasone in relapsed refractory multiple myeloma after lenalidomide treatment failure. Br J Haematol. 2019 Oct 6. doi: 10.1111/bjh.16213. Siegel DS, Schiller GJ, Song KW, Agajanian R, Stockerl-Goldstein K, Kaya H, Sebag M, Samaras C, Malek E, Talamo G, Seet CS, Mouro J, Pierceall WE, Zafar F, Chung W, Srinivasan S, Agarwal A, Bahlis NJ
- Br J Haematol Impact of age, sex, ethnicity, socio-economic deprivation and novel pharmaceuticals on the overall survival of patients with multiple myeloma in New Zealand. Br J Haematol. 2019 Oct 4. doi: 10.1111/bjh.16238. Chan HSH, Milne RJ
- Br J Haematol An upsurge of the serum free light chains as a possible missing link in tumour lysis syndrome in multiple myeloma. Br J Haematol. 2019 Oct 1. doi: 10.1111/bjh.16231. Yavorkovsky LL, Jing W, Baker R
- Haematologica RAL GTPases mediate multiple myeloma cell survival and are activated independently of oncogenic RAS. Haematologica. 2019 Oct 10. pii: haematol.2019.223024. doi: 10.3324/haematol.2019.223024. Seibold M, Stühmer T, Kremer N, Mottok A, Scholz CJ, Schlosser A, Leich E, Holzgrabe U, Brünnert D, Barrio S, Kortüm KM, Solimando AG, Chatterjee M, Einsele H, Rosenwald A, Bargou RC, Steinbrunn T
- Haematologica Multiple myeloma exploits Jagged1 and Jagged2 to promote intrinsic and bone marrow-dependent drug resistance. Haematologica. 2019 Oct 3. pii: haematol.2019.221077. doi: 10.3324/haematol.2019.221077. Colombo M, Garavelli S, Mazzola M, Platonova N, Giannandrea D, Colella R, Apicella L, Lancellotti M, Lesma E, Ancona S, Palano MT, Barbieri M, Taiana E, Lazzari E, Basile A, Turrini M, Pistocchi A, Neri A, Chiaramonte R
- Haematologica Lenalidomide-based induction and maintenance in elderly newly diagnosed multiple myeloma patients: updated results of the EMN01 randomized trial. Haematologica. 2019 Oct 3. pii: haematol.2019.226407. doi: 10.3324/haematol.2019.226407. Bringhen S, D'Agostino M, Paris L, Ballanti S, Pescosta N, Spada S, Pezzatti S, Grasso M, Rota-Scalabrini D, De Rosa L, Pavone V, Gazzera G, Aquino S, Poggiu M, Santoro A, Gentile M, Baldini L, Petrucci MT, Tosi P, Marasca R, Cellini C, Palumbo A, Falco P, Hájek R, Boccadoro M, Larocca A
- Haematologica Identification of PIKfyve kinase as a target in multiple myeloma. Haematologica. 2019 Oct 3. pii: haematol.2019.222729. doi: 10.3324/haematol.2019.222729. Bonolo De Campos C, Zhu YX, Sepetov N, Romanov S, Bruins LA, Shi CX, Stein CK, Petit JL, Polito AN, Sharik ME, Meermeier EW, Ahmann GJ, Lopez Armenta ID, Kruse J, Bergsagel PL, Chesi M, Meurice N, Braggio E, Stewart AK
- Haematologica Histone deacetylase inhibition in combination with MEK or BCL-2 inhibition in multiple myeloma. 104(10):2061-2074 Ramakrishnan VG, Miller KC, Macon EP, Kimlinger TK, Haug J, Kumar S, Gonsalves WI, Rajkumar SV, Kumar SK
- Haematologica The transcriptomic profile of CD138+ cells from patients with early progression from smoldering to active multiple myeloma remains substantially unchanged. 104(10):e465-e469 Storti P, Agnelli L, Palma BD, Todoerti K, Marchica V, Accardi F, Sammarelli G, Deluca F, Toscani D, Costa F, Vicario E, Todaro G, Martella E, Neri A, Giuliani N
- J Clin Oncol Randomized Trial of Lenalidomide Versus Observation in Smoldering Multiple Myeloma. J Clin Oncol. 2019 Oct 25:JCO1901740. doi: 10.1200/JCO.19.01740. Lonial S, Jacobus S, Fonseca R, Weiss M, Kumar S, Orlowski RZ, Kaufman JL, Yacoub AM, Buadi FK, O'Brien T, Matous JV, Anderson DM, Emmons RV, Mahindra A, Wagner LI, Dhodapkar MV, Rajkumar SV
- Lancet Haematol Multitargeted CAR T-cell therapy in multiple myeloma. 6(10):e494-e495 Susanibar Adaniya S, Garfall AL
- Lancet Haematol A combination of humanised anti-CD19 and anti-BCMA CAR T cells in patients with relapsed or refractory multiple myeloma: a single-arm, phase 2 trial. 6(10):e521-e529 Yan Z, Cao J, Cheng H, Qiao J, Zhang H, Wang Y, Shi M, Lan J, Fei X, Jin L, Jing G, Sang W, Zhu F, Chen W, Wu Q, Yao Y, Wang G, Zhao J, Zheng J, Li Z, Xu K
- Lancet Oncol Reducing infection-related morbidity and mortality in patients with myeloma. Lancet Oncol. 2019 Oct 23. pii: S1470-2045(19)30649-7. doi: 10.1016/S1470-2045(19)30649-7. Ramasamy K
- Lancet Oncol Levofloxacin prophylaxis in patients with newly diagnosed myeloma (TEAMM): a multicentre, double-blind, placebo-controlled, randomised, phase 3 trial. Lancet Oncol. 2019 Oct 23. pii: S1470-2045(19)30506-6. doi: 10.1016/S1470-2045(19)30506-6. Drayson MT, Bowcock S, Planche T, Iqbal G, Pratt G, Yong K, Wood J, Raynes K, Higgins H, Dawkins B, Meads D, Hulme CT, Monahan I, Karunanithi K, Dignum H, Belsham E, Neilson J, Harrison B, Lokare A, Campbell G, Hamblin M, Hawkey P, Whittaker AC, Low E, Dunn JA; TEAMM Trial Management Group and Trial Investigators
- Lancet Oncol Selinexor-dexamethasone for refractory multiple myeloma. 20(10):e560 Stirrups R
- Leukemia The relative importance of factors predicting outcome for myeloma patients at different ages: results from 3894 patients in the Myeloma XI trial. Leukemia. 2019 Oct 14. doi: 10.1038/s41375-019-0595-5. Pawlyn C, Cairns D, Kaiser M, Striha A, Jones J, Shah V, Jenner M, Drayson M, Owen R, Gregory W, Cook G, Morgan G, Jackson G, Davies F
- Leukemia Transcriptional profiling of circulating tumor cells in multiple myeloma: a new model to understand disease dissemination. Leukemia. 2019 Oct 8. doi: 10.1038/s41375-019-0588-4. Garcés JJ, Simicek M, Vicari M, Brozova L, Burgos L, Bezdekova R, Alignani D, Calasanz MJ, Growkova K, Goicoechea I, Agirre X, Pour L, Prosper F, Rios R, Martinez-Lopez J, Millacoy P, Palomera L, Del Orbe R, Perez-Montaña A, Garate S, Blanco L, Lasa M, Maiso P, Flores-Montero J, Sanoja-Flores L, Chyra Z, Vdovin A, Sevcikova T, Jelinek T, Botta C, El Omri H, Keats J, Orfao A, Hajek R, San-Miguel JF, Paiva B
- Leukemia DNA methyltransferase inhibitors upregulate CD38 protein expression and enhance daratumumab efficacy in multiple myeloma. Leukemia. 2019 Oct 8. doi: 10.1038/s41375-019-0587-5. Choudhry P, Mariano MC, Geng H, Martin TG 3rd, Wolf JL, Wong SW, Shah N, Wiita AP
- Leukemia Monitoring the cytogenetic architecture of minimal residual plasma cells indicates therapy-induced clonal selection in multiple myeloma. Leukemia. 2019 Oct 7. doi: 10.1038/s41375-019-0590-x. An G, Yan Y, Xu Y, Mao X, Liu J, Fan H, Wang Q, Du C, Li Z, Yi S, Lv R, Deng S, Sui W, Fu M, Hao M, Huang W, Zou D, Zhao Y, Yuan C, Du X, Wang J, Cheng T, Tai YT, Munshi NC, Qiu L
- Leukemia Relapsed refractory multiple myeloma: a comprehensive overview. 33(10):2343-2357 Bazarbachi AH, Al Hamed R, Malard F, Harousseau JL, Mohty M
SCT
- Br J Haematol Brentuximab vedotin for the treatment of patients with relapsed or refractory Hodgkin lymphoma after autologous stem cell transplantation. Br J Haematol. 2019 Oct 6. doi: 10.1111/bjh.16201. Kaloyannidis P, Hertzberg M, Webb K, Zomas A, Schrover R, Hurst M, Jacob I, Nikoglou T, Connors JM
- Br J Haematol Respiratory viral infections prior to and after allogeneic haematopoietic cell transplantation. Br J Haematol. 2019 Oct 1. doi: 10.1111/bjh.16215. Passweg JR, Khanna N, Halter J
- Haematologica Mental fatigue after allogeneic hematopoietic stem cell transplantation is associated with cognitive dysfunction, but not central nervous system inflammation. Haematologica. 2019 Oct 24. pii: haematol.2019.225326. doi: 10.3324/haematol.2019.225326. Boberg E, Kadri N, Winterling J, Davies LC, Björklund A, Msghina M, Iacobaeus E, Le Blanc K
- Haematologica Yttrium-90-labeled anti-CD45 antibody followed by a reduced-intensity hematopoietic cell transplantation for patients with relapsed/refractory leukemia or myelodysplasia. Haematologica. 2019 Oct 3. pii: haematol.2019.229492. doi: 10.3324/haematol.2019.229492. Vo P, Gooley TA, Rajendran JG, Fisher DR, Orozco JJ, Green DJ, Gopal AK, Haaf R, Nartea M, Storb R, Appelbaum FR, Press OW, Pagel JM, Sandmaier BM
- J Clin Oncol Human Herpesvirus 6B and Lower Respiratory Tract Disease After Hematopoietic Cell Transplantation. 37(29):2670-2681 Hill JA, Vande Vusse LK, Xie H, Chung EL, Yeung CCS, Seo S, Stevens-Ayers T, Fisher CE, Huang ML, Stewart FM, Jerome KR, Zerr DM, Corey L, Leisenring WM, Boeckh M
- Lancet Haematol Role of HLA-B exon 1 in graft-versus-host disease after unrelated haemopoietic cell transplantation: a retrospective cohort study. Lancet Haematol. 2019 Oct 25. pii: S2352-3026(19)30208-X. doi: 10.1016/S2352-3026(19)30208-X. Petersdorf EW, Carrington M, O'hUigin C, Bengtsson M, De Santis D, Dubois V, Gooley T, Horowitz M, Hsu K, Madrigal JA, Maiers MJ, Malkki M, McKallor C, Morishima Y, Oudshoorn M, Spellman SR, Villard J, Stevenson P; International Histocompatibility Working Group in Hematopoietic Cell Transplantation
- Lancet Haematol Treosulfan or busulfan plus fludarabine as conditioning treatment before allogeneic haemopoietic stem cell transplantation for older patients with acute myeloid leukaemia or myelodysplastic syndrome (MC-FludT.14/L): a randomised, non-inferiority, phase 3 trial. Lancet Haematol. 2019 Oct 9. pii: S2352-3026(19)30157-7. doi: 10.1016/S2352-3026(19)30157-7. Beelen DW, Trenschel R, Stelljes M, Groth C, Masszi T, Reményi P, Wagner-Drouet EM, Hauptrock B, Dreger P, Luft T, Bethge W, Vogel W, Ciceri F, Peccatori J, Stölzel F, Schetelig J, Junghanß C, Grosse-Thie C, Michallet M, Labussiere-Wallet H, Schaefer-Eckart K, Dressler S, Grigoleit GU, Mielke S, Scheid C, Holtick U, Patriarca F, Medeot M, Rambaldi A, Micò MC, Niederwieser D, Franke GN, Hilgendorf I, Winkelmann NR, Russo D, Socié G, Peffault de Latour R, Holler E, Wolff D, Glass B, Casper J, Wulf G, Menzel H, Basara N, Bieniaszewska M, Stuhler G, Verbeek M, Grass S, Iori AP, Finke J, Benedetti F, Pichlmeier U, Hemmelmann C, Tribanek M, Klein A, Mylius HA, Baumgart J, Dzierzak-Mietla M, Markiewicz M
- Leukemia Hematopoietic stem cell transplantation for adults with T-cell lymphoblastic lymphoma: can we successfully step into the era of precision medicine? Leukemia. 2019 Oct 22. doi: 10.1038/s41375-019-0608-4. Young KH
- Leukemia HLA-matched and HLA-haploidentical allogeneic CD19-directed chimeric antigen receptor T-cell infusions are feasible in relapsed or refractory B-cell acute lymphoblastic leukemia before hematopoietic stem cell transplantation. Leukemia. 2019 Oct 18. doi: 10.1038/s41375-019-0610-x. Jin X, Cao Y, Wang L, Sun R, Cheng L, He X, Xiao X, Jiang Y, Li Q, Zhang H, Lu W, Lyu C, Jiang Y, Meng J, Zhao M
- Leukemia Generation and infusion of multi-antigen-specific T cells to prevent complications early after T-cell depleted allogeneic stem cell transplantation-a phase I/II study. Leukemia. 2019 Oct 17. doi: 10.1038/s41375-019-0600-z. Roex MCJ, van Balen P, Germeroth L, Hageman L, van Egmond E, Veld SAJ, Hoogstraten C, van Liempt E, Zwaginga JJ, de Wreede LC, Meij P, Vossen ACTM, Danhof S, Einsele H, Schaafsma MR, Veelken H, Halkes CJM, Jedema I, Falkenburg JHF
- Leukemia PMN-MDSC are a new target to rescue graft-versus-leukemia activity of NK cells in haplo-HSC transplantation. Leukemia. 2019 Oct 4. doi: 10.1038/s41375-019-0585-7. Tumino N, Besi F, Di Pace AL, Mariotti FR, Merli P, Li Pira G, Galaverna F, Pitisci A, Ingegnere T, Pelosi A, Quatrini L, Munari E, Locatelli F, Moretta L, Vacca P
- Leukemia Hematopoietic stem cell transplantation for children with acute myeloid leukemia-results of the AML SCT-BFM 2007 trial. Leukemia. 2019 Oct 2. doi: 10.1038/s41375-019-0584-8. Sauer MG, Lang PJ, Albert MH, Bader P, Creutzig U, Eyrich M, Greil J, Gruhn B, Holter W, Klingebiel T, Kremens B, von der Leyen H, Mauz-Körholz C, Meisel R, Mischke K, Müller I, Niemeyer CM, Peters C, Pohler C, Reinhardt D, Burkhardt B, Schlegel PG, Schulz AS, Schrum J, Sedlacek P, Strahm B, Woessmann W, Handgretinger R, Zimmermann M, Borkhardt A
- Leukemia Safety and feasibility of chimeric antigen receptor T cell therapy after allogeneic hematopoietic cell transplantation in relapsed/ refractory B cell non-Hodgkin lymphoma. 33(10):2540-2544 Jain T, Sauter CS, Shah GL, Maloy MA, Chan J, Scordo M, Avecilla ST, Batlevi Y, Dahi PB, Batlevi CW, Lia Palomba M, Giralt SA, Perales MA
HSC
- Blood Resveratrol trimer enhances gene delivery to hematopoietic stem cells by reducing antiviral restriction at endosomes. 134(16):1298-1311 Stosh Ozog, Nina D. Timberlake, Kip Hermann, Olivia Garijo, Kevin G. Haworth, Guoli Shi, Christopher M. Glinkerman, Lauren E. Schefter, Saritha D’Souza, Elizabeth Simpson, Gabriella Sghia-Hughes, Raymond R. Carillo, Dale L. Boger, Hans-Peter Kiem, Igor Slukvin, Byoung Y. Ryu, Brian P. Sorrentino, Jennifer E. Adair, Scott A. Snyder, Alex A. Compton, Bruce E. Torbett
- Blood Molecular interactome between HSCs and their niches. 134(15):1197-1198 Simón Méndez-Ferrer
- Blood Prospective isolation of nonhematopoietic cells of the niche and their differential molecular interactions with HSCs. 134(15):1214-1226 Nicole Mende, Adrien Jolly, Gulce I. Percin, Marko Günther, Maria Rostovskaya, Shyam M. Krishnan, Robert A. J. Oostendorp, Andreas Dahl, Konstantinos Anastassiadis, Thomas Höfer, Claudia Waskow
- Blood The KDM4/JMJD2 histone demethylases are required for hematopoietic stem cell maintenance. 134(14):1154-1158 Agger K, Nishimura K, Miyagi S, Messling JE, Rasmussen KD, Helin K
- Haematologica Mental fatigue after allogeneic hematopoietic stem cell transplantation is associated with cognitive dysfunction, but not central nervous system inflammation. Haematologica. 2019 Oct 24. pii: haematol.2019.225326. doi: 10.3324/haematol.2019.225326. Boberg E, Kadri N, Winterling J, Davies LC, Björklund A, Msghina M, Iacobaeus E, Le Blanc K
- Lancet Haematol Treosulfan or busulfan plus fludarabine as conditioning treatment before allogeneic haemopoietic stem cell transplantation for older patients with acute myeloid leukaemia or myelodysplastic syndrome (MC-FludT.14/L): a randomised, non-inferiority, phase 3 trial. Lancet Haematol. 2019 Oct 9. pii: S2352-3026(19)30157-7. doi: 10.1016/S2352-3026(19)30157-7. Beelen DW, Trenschel R, Stelljes M, Groth C, Masszi T, Reményi P, Wagner-Drouet EM, Hauptrock B, Dreger P, Luft T, Bethge W, Vogel W, Ciceri F, Peccatori J, Stölzel F, Schetelig J, Junghanß C, Grosse-Thie C, Michallet M, Labussiere-Wallet H, Schaefer-Eckart K, Dressler S, Grigoleit GU, Mielke S, Scheid C, Holtick U, Patriarca F, Medeot M, Rambaldi A, Micò MC, Niederwieser D, Franke GN, Hilgendorf I, Winkelmann NR, Russo D, Socié G, Peffault de Latour R, Holler E, Wolff D, Glass B, Casper J, Wulf G, Menzel H, Basara N, Bieniaszewska M, Stuhler G, Verbeek M, Grass S, Iori AP, Finke J, Benedetti F, Pichlmeier U, Hemmelmann C, Tribanek M, Klein A, Mylius HA, Baumgart J, Dzierzak-Mietla M, Markiewicz M
- Leukemia Thiopurine-mediated impairment of hematopoietic stem and leukemia cells in Nudt15R138C knock-in mice. Leukemia. 2019 Oct 24. doi: 10.1038/s41375-019-0583-9. Tatsumi G, Kawahara M, Imai T, Nishishita-Asai A, Nishida A, Inatomi O, Yokoyama A, Kakuta Y, Kito K, Andoh A
- Leukemia Hematopoietic stem cell transplantation for adults with T-cell lymphoblastic lymphoma: can we successfully step into the era of precision medicine? Leukemia. 2019 Oct 22. doi: 10.1038/s41375-019-0608-4. Young KH
- Leukemia HLA-matched and HLA-haploidentical allogeneic CD19-directed chimeric antigen receptor T-cell infusions are feasible in relapsed or refractory B-cell acute lymphoblastic leukemia before hematopoietic stem cell transplantation. Leukemia. 2019 Oct 18. doi: 10.1038/s41375-019-0610-x. Jin X, Cao Y, Wang L, Sun R, Cheng L, He X, Xiao X, Jiang Y, Li Q, Zhang H, Lu W, Lyu C, Jiang Y, Meng J, Zhao M
- Leukemia PMN-MDSC are a new target to rescue graft-versus-leukemia activity of NK cells in haplo-HSC transplantation. Leukemia. 2019 Oct 4. doi: 10.1038/s41375-019-0585-7. Tumino N, Besi F, Di Pace AL, Mariotti FR, Merli P, Li Pira G, Galaverna F, Pitisci A, Ingegnere T, Pelosi A, Quatrini L, Munari E, Locatelli F, Moretta L, Vacca P
- Leukemia Hematopoietic stem cell transplantation for children with acute myeloid leukemia-results of the AML SCT-BFM 2007 trial. Leukemia. 2019 Oct 2. doi: 10.1038/s41375-019-0584-8. Sauer MG, Lang PJ, Albert MH, Bader P, Creutzig U, Eyrich M, Greil J, Gruhn B, Holter W, Klingebiel T, Kremens B, von der Leyen H, Mauz-Körholz C, Meisel R, Mischke K, Müller I, Niemeyer CM, Peters C, Pohler C, Reinhardt D, Burkhardt B, Schlegel PG, Schulz AS, Schrum J, Sedlacek P, Strahm B, Woessmann W, Handgretinger R, Zimmermann M, Borkhardt A
- Leukemia Kdm6b regulates context-dependent hematopoietic stem cell self-renewal and leukemogenesis. 33(10):2506-2521 Mallaney C, Ostrander EL, Celik H, Kramer AC, Martens A, Kothari A, Koh WK, Haussler E, Iwamori N, Gontarz P, Zhang B, Challen GA
Anemia
- Br J Haematol Management of anaemia in pre-term infants. Br J Haematol. 2019 Oct 6. doi: 10.1111/bjh.16233. Saito-Benz M, Flanagan P, Berry MJ
- Br J Haematol Hydroxycarbamide and white matter integrity in pediatric sickle cell disease: Commentary to accompany: Hydroxycarbamide treatment in children with sickle cell anaemia is associated with more intact white matter integrity: a quantitative MRI study. 187(2):141-143 Lance EI, Jordan LC
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